Word: shrinking
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...politics, 1996 might as well be the last century. The hallowed game plan--hold your base, then hook the swing voters--gets trickier with each election, as the loyal party bases shrink and the big clump of independents grows. But it is especially hard for Gore this year. Gore's base is spoiled and soft after eight years in power--in one poll he drew only 78% of core Democrats. Bush's is so hungry to win it put its differences aside long ago: Bush has the support of 95% of the G.O.P. base, and so has been able...
...head and neck cancer. While traditional gene therapy aims to replace defective genes, Onyx-015 trades on the genetic difference between cancerous and normal cells to hunt and kill only the cancer. In a study, 63% of 30 patients who received Onyx-015 along with chemotherapy saw their tumors shrink by at least half. After five months, none of the tumors had grown back. Doctors hope that Onyx-015 will also prove effective against ovarian, pancreatic and other aggressive cancers...
...inheriting the business, to develop the company so it could thrive in the coming century. She knew it wouldn't be easy: her dad was irascible, and the place was "crawling with relatives," not all of them productive. Fortunately, she was able turn to an old friend, "a super shrink who encouraged me to accept my own perceptions and not to assume I was the one who was crazy." Ultimately she became president of an increasingly successful company. But she never told her father about the therapy. "He would have been furious," she admits, "if he knew any analysis...
...most straightforward approach to fighting Alzheimer's plaques is to target their main ingredient, a protein called beta amyloid. Last summer scientists from Elan Pharmaceuticals, a biotech firm located in Ireland, reported that they had developed a vaccine that could shrink the plaques--at least in mice. Here the idea is to prime the immune system to treat amyloid proteins just as it would any foreign invader and target them for destruction. The concept is somewhat counterintuitive, since most researchers believe that at least part of the damage in Alzheimer's disease is caused by the immune system's overreaction...
...percent. As far as the market is concerned, that's bad, but not very. More dramatically, the economy created only 11,000 non-farm jobs - a fraction of the 260,000 expected by analysts - and that's very good. But the pool of available labor continued to shrink, by some 3 percent, and that's not so good for wage and inflationary pressures...