Word: sildenafil
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...banned in Europe and Asia. What to avoid: aristolochic acid, comfrey, androstenedione, chaparral, germander, kava, bitter orange, organ or gland extracts, lobelia, pennyroyal oil, scullcap and yohimbe. In addition, the FDA says, consumers should steer clear of supplements called Actra-Rx and Yilishen, which contain prescription-strength levels of sildenafil, the active ingredient in Viagra. It can lower blood pressure to dangerous levels...
...months. Some urologists bought rubber stamps so they could churn out prescriptions, and equally excited patients booked advance appointments. Despite all that, Viagra, the world's most popular prescription party drug, didn't have much of a party the day the FDA gave its much-anticipated O.K. to sildenafil citrate. That's because giant pharmaceutical companies--even ones that get a license from the government to print money in blue-pill form--aren't really party places. "We had a nice dinner that night," admits Dr. Ian Osterloh, who directed the development of the impotence treatment...
...Mesher's story suggests, and many doctors insist, more isn't necessarily more with Viagra. Known to chemists by the less evocative name of sildenafil (the word Viagra, redolent of both "vigor" and "Niagara," had been kicking around Pfizer for years, a brand name in search of a product), the drug began life as a heart medication designed to treat angina by increasing blood flow to the heart. Sildenafil, it turned out, wasn't so good at opening coronary arteries, but happy test subjects did notice increased blood flow to their penises, a side effect brought to Pfizer's attention...
Doctors are concerned that an anti-impotence pill could be subject to widespread abuse. Reports indicate that some Hollywood bedroom athletes have already tapped an underground market for an injectable erection drug. The danger is that otherwise healthy men will take sildenafil to bolster their sexual performance and then become psychologically addicted, unable to achieve an erection without...
...researchers have detected very few side effects from sildenafil. In a twist on an old joke, however, a handful of men complained that the medicine gave them headaches. Pfizer researchers are betting that won't prove a strong impediment, and they expect sildenafil to come before the U.S. Food and Drug Administration for review by the end of next year...