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Five years before the triumph of the Harvard group, Organic Chemist Har Gobind Khorana, a Nobel laureate now working at M.I.T., had synthesized a yeast gene, the simplest gene yet made. Already aware of the sequence of the 77 "code letters," or nucleotides, in the DNA of the gene, Khorana painstakingly "assembled" the letters one at a tune in the proper order to produce a synthetic unit. The rabbit gene is at least eight times as large, containing about 650 nucleotides strung together in a sequence that scientists have not yet completely determined. Clearly the Harvard group could not follow...

Author: /time Magazine | Title: Science: The Gene Makers | 12/22/1975 | See Source »

...simplest level, the problem manifests itself in language. Words are generalizations designed to describe ideal types. Liberal theory assumes that man can know the essence of every object, but words limit the degree to which he can describe a thing; he can never perfectly describe any particular object...

Author: By Mark J. Penn, | Title: Escaping the Prison House of Liberalism | 12/5/1975 | See Source »

None of the contestants used beans. "That," sniffed one chili head, "would be like mixing cognac and Dr. Pepper." In fact, the simplest recipe proved best in the view of a panel of judges that included Actors Ernest Borgnine, William Conrad and McCulloch Oil President C.V. Wood, retired, undefeated world chili champ. Joe DeFrates, 67, of Springfield, Ill., winner of the California cookoff, concocted his "horse-and-buggy" chili from lean beef, peppers and his own chili powder. The Texas champion, Susie Watson of Houston, used a similar recipe, plus an arcane spice derived from pine cones. Even in Texas...

Author: /time Magazine | Title: Modern Living: Montezuma Manna | 11/17/1975 | See Source »

...attitude with which to view an academic field that is so broad-based. Besides, Isselbacher says, "The natural history of the disease is such that, it isn't like pneumonia, that in just two weeks you can find out whether Drug A is better than Drug B." Even the simplest clinical experiments may require a five-year waiting period...

Author: By Philip Weiss, | Title: Will Harvard Cure Cancer? | 9/15/1975 | See Source »

...most effective solution may be the simplest: for U.S. multinationals simply to say no to foreign demands for bribes. Unquestionably, they would lose some contracts to French, West German, Japanese and other foreign competitors and perhaps to some U.S.-based rivals too. Yet despite intense pressure, such big U.S. companies as W.R. Grace, Phelps Dodge, International Paper and IBM have established reputations overseas for refusing to go along with bribery and generally find they can sell on the appeal of their products and services...

Author: /time Magazine | Title: SCANDALS: Lifting the Lid on Some Mysterious Money | 6/23/1975 | See Source »

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