Word: simplex
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...nearly 90% of adults have been exposed to the herpes simplex virus-1 (HSV-1), which causes cold sores. People are usually infected as children, but many never have symptoms. For those who do, however, cold sores are a painful and permanent nuisance, always erupting in the same location, at the original site of infection on the lips or mouth. Once HSV-1 enters the body it hunkers down for life, most of the time hiding dormant in the cranial nerves near the spine. The virus can be triggered by outside stress, such as exposure to sunlight, a fever...
...Cullen believes that a drug could be developed to block the microRNA that suppress HSV-1 into latency; once it's active, acyclovir can be used to destroy the virus permanently. Cullen suggests that this new research may also eventually be applied to other latent viruses, such as herpes simplex virus-2 (HSV-2), which causes genital herpes, or the chicken pox virus, which causes shingles in adults. Cullen warns that some patients, especially those suffering genital herpes, may have to take acyclovir on a regular basis (HSV-2 is a hardier virus), but for people with...
HERPES HEARTACHE Hold that kiss! A provocative but still preliminary study suggests that herpes simplex virus Type 1 (the virus that causes cold sores and fever blisters) may be linked to heart disease. Researchers found that seniors with a history of herpes were twice as likely to suffer a heart attack as those who never had a cold sore...
...father had been afflicted by this strange ailment, but I knew little about shingles until I did some digging. I learned that shingles could be thought of as the revenge of the chicken pox, or of varicella-zoster, the virus behind this childhood disease. A close cousin of herpes simplex, which causes cold sores, varicella-zoster can be beaten back by the immune system but never eradicated. Like a bandit pursued by a posse, it retreats to a safe haven--bundles of nerve cells in the spinal cord or cranium. There varicella-zoster lies dormant, usually for decades...
Bernard Roizman has arrived from the University of Chicago to pontificate on "Herpes Simplex Virus Versus the Host Cell: The Strategy of Conquest." In the MEC Amphitheater, MEC Educational Building...