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...early-onset Alzheimer's all lead to an overproduction of beta amyloid. But the genes involved in the bulk of cases, Selkoe strongly suspects, are more likely to do with faulty clearance mechanisms that aren't doing a good enough job flushing out the plaques. A sink can overflow, he observes, for two reasons--if the faucet is too wide and the drain too narrow...

Author: /time Magazine | Title: The New Science of Alzheimer's | 7/17/2000 | See Source »

Many emotions surround memory loss, the worst of which is fear [SCIENCE, June 12]. I was rapidly losing my memory before medication that helped me was prescribed. One day my husband gently asked me if there was a reason I had hung up the phone in the sink. It was funny and a little scary, but what I didn't share with him was that while on the phone with our Chihuahua on my lap, I had tried to hang up the dog. Now I'm much better. I faced the fear and got help. DARLYNE TRAUM STROHMENGER West Seneca...

Author: /time Magazine | Title: Letters: Jul. 3, 2000 | 7/3/2000 | See Source »

...Cheerful Conservative." I admire Podhoretz immensely for the clarity, decency, and, shall we say, ruthlessness of his thought, but "cheerful" is not the first word he brings to my mind. A few years ago at a dinner in a highly WASP old club in New York, I watched Podhoretz sink his teeth (figuratively speaking) into a supercilious liberal's calf in the way a very focused dog goes after the mailman. He did not let go for three hours or so. I forget what they were fighting about...

Author: /time Magazine | Title: Lance Morrow Sings of America | 7/3/2000 | See Source »

While we note the dangerous fragility of our hasty creations, we race blindly ahead. Too bad our technological hubris didn't sink with the Titanic. PATRICK DUBOIS London, Canada...

Author: /time Magazine | Title: Letters: Jun. 5, 2000 | 6/5/2000 | See Source »

...embody - and amplify - all that's wrong with society. Sure, other public figures, such as actors and politicians, are also more open to media censure than they were in decades past (just imagine the wreckage that would have ensued had the current Washington press corps been able to sink its hooks into the womanizing ways of JFK), but pro athletes, compared to politicians and entertainers, are less insulated from the press and far less media-savvy...

Author: /time Magazine | Title: Hey, They're Athletes, Not Philosophers | 5/30/2000 | See Source »

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