Word: sisters
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...what did you do? I think anybody who has been through a shock like that, you know how you feel. Your body is just really numb. My sister kind of came in and took over. By now, the word was trickling out, and it was just chaos in the church. I have to tell you, it looked a lot like Sex and the City, when Big wouldn't marry Carrie. My people were rallying for me, and my sister said things in the church she shouldn't have said. I'm sure bad words. She was yelling...
...Stephanie Yarber, who received a diagnosis of premature ovarian failure at age 14, conceiving children the old-fashioned way was a life's wish. In 2003, after several unsuccessful - and costly - courses of in vitro fertilization (IVF) using her identical-twin sister's donated eggs, Yarber began looking into other options. There was adoption, of course. But there was also a riskier experimental alternative: ovarian transplantation...
...Sherman Silber of the Infertility Center of St. Louis, who in the late 1970s had performed the first successful testicular transplant between male identical twins, allowing the once infertile brother to father five children. Yarber wondered if the same doctor could do a similar procedure between her and her sister. Yarber's sister, who had three daughters and didn't plan to have any more children, eagerly agreed to help. "She wouldn't have said no," Yarber says. "I knew that." (See the top 10 medical breakthroughs of the past year...
...Yarber's microsurgical procedure involved the transplantation from her sister to her of a thin strip of cortical tissue - the part of the ovary that produces eggs. (The leftover strips of egg-producing tissue from the harvested ovary were frozen and stored for future use.) Within months, Yarber began menstruating. In September 2004, just five months after the transplant, she was pregnant. Five years and another tissue transplant later, Yarber has two daughters, ages 3½ years and 10 months, and is trying for a third child. Owing in large part to Yarber's willingness to talk about her experience...
...Silber tried the same procedure on a set of nonidentical twins for the first time. The recipient of the ovary, a San Francisco woman named Joy Lagos, had become infertile after cancer treatment. But the hope was that because Lagos had received a bone-marrow transplant from her older sister as part of that treatment - which transformed Lagos' immune system into a chimera, or hybrid, of her sister's and her own cells - her combination immune system would stand a far better chance of accepting her sister's ovary without the need for long-term immunosuppressant drugs...