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...offense, as the visitors put up eight more runs over the next two innings. Most of the damage came from O’Hara in the cleanup spot, who belted doubles in the first and second innings and a bases-clearing triple in the third for a total of six...
...squads combined for only one hit through the first two innings, but Harvard would take advantage of some control issues by Yale’s Holly Gutterud to knock in six runs in the top of the third frame...
Yale’s Gutterud pitched a complete game but allowed four of her six hits and two of her four walks in the decisive third inning...
First, the current treatment regimen requires patients take a cocktail of four drugs, all nearly half a century old, for at least six months. The logistical and financial hurdles associated with paying for and completing treatment, however, virtually guarantee noncompliance and relapse. Second, in a cascade effect, noncompliance selects for drug-resistant strains of the mutated pathogen, precipitating the rise of multi-drug resistant and extremely drug-resistant tuberculosis. Treatment for drug-resistant TB with second-line drugs is astronomically more expensive, more time-intensive, and associated with more toxic side effects. Third, the rise of TB and human immunodeficiency...
...Instead of developing new drugs one-by-one, the Critical Path to TB Regimens Initiative would bring together drug developers, under a “patients-first” commitment, to test their compounds together as an entirely new four-drug combination—a process that would take six, rather than 24, years...