Word: slamon
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Dates: during 2000-2009
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...that cause them to grow abnormally. Eventually the cells develop into DCIS. The good thing about dcis cells is that they haven't spread beyond the milk duct. The bad thing is that they are malignant. "Some people call DCIS precancer, but it's not precancer," says Dr. Dennis Slamon, director of breast-cancer research at the UCLA School of Medicine. "It's preinvasive. It's cancer that hasn't invaded outside the breast ducts...
Herceptin is only a beginning, says UCLA's Slamon, who identified the HER2 receptor. There are bound to be other cancer proteins that pharmaceutical manufacturers can use as targets as they develop new, more selective drugs. "Using a combination of [these kinds of] therapies earlier in the disease could have a dramatic impact on outcomes," Slamon says...
...problem with having just one chemotherapy drug is that it limits your options. The cells that line the intestine are so used to acting as a garbage dump, explains Dr. Dennis Slamon of UCLA, that the ones "that eventually become malignant are less susceptible to chemotherapy...