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Bradfield's doctor put her in touch with UCLA's Slamon, who was testing a brand-new antibody that targeted the HER-2/neu protein. Although Slamon was using the antibody in combination with chemotherapy--and Bradfield was loath to go back to chemo--the combined therapy proved miraculous in her case. Sixteen small tumors in her lungs melted away. By 1993 she was in remission, and still is. "I got to be at my son's wedding," she exults. "The gift is that I'm here...

Author: /time Magazine | Title: Molecular Revolution | 5/18/1998 | See Source »

...Because of the early success with chemotherapy in some forms of leukemias and lymphomas," says Dr. Dennis Slamon, of the Revlon/UCLA Women's Cancer Research Program, "we have been slugging at cancer that way for 25 years. We didn't make any significant inroads, and in some cases, we ended up killing people. Now we are beginning to look specifically at what's broken in a cancer cell and trying to target that...

Author: /time Magazine | Title: Molecular Revolution | 5/18/1998 | See Source »

...outraged," Glaspy recalls. He believed he still had room to work the system and persuade Health Net to pay for the treatment. He felt guilty about costing the unit so much money and resented Slamon's interference in an area where he, Glaspy, was the expert. That night he wrote a letter of resignation. Later, however, he reconsidered. "It took me four or five days to cool...

Author: /time Magazine | Title: MEDICAL CARE: THE SOUL OF AN HMO | 1/22/1996 | See Source »

...Slamon says he made the decision to pay for the transplant after discovering that Christy by then had already undergone the initial marrow harvest. "We should not have taken her halfway into the stream without being prepared to take her all the way across," he says. He insists that the decision was his alone, and not the result of any coercion from Health...

Author: /time Magazine | Title: MEDICAL CARE: THE SOUL OF AN HMO | 1/22/1996 | See Source »

Last October the arbitration panel hearing Christy's case determined that Health Net should indeed have paid for the transplant. It also found the company had crossed the line in interfering with the doctor-patient relationship, specifically when Health Net officials phoned Christy's local oncologist and UCLA's Slamon. The latter call "was more heavy-handed" than either man was willing to admit, the panel concluded, and had been made to "influence or intimidate" UCLA and its doctors. Two of the three panelists further saw this interference as constituting "intentional infliction of emotional distress" on the deMeurerses because...

Author: /time Magazine | Title: MEDICAL CARE: THE SOUL OF AN HMO | 1/22/1996 | See Source »

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