Word: sloan
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Dates: during 1940-1949
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...long ago, Memorial's doctors noticed that cancer patients, often reacted well after a serious operation, but died a few days later for no apparent reason. Sloan-Kettering's research men went to work to find an explanation, found that in such cases the patients had died because of a deficiency of potassium in the blood. When potassium was added in new cases, the patients picked up quickly and survived the operation. Dr. Rhoads believes that such improved surgery and treatment, combined with sufficiently early diagnosis, may save from cancer one-third to one-half of the people...
...hurts one generally hurts the other. Still, the gangster cells have differences. The very fact that they grow rapidly in a chemical medium, the blood, in which normal cells grow slowly, is sufficient proof that they are different. To find and exploit the differences is the chief goal of Sloan-Kettering Institute. The problem is being attacked at all levels-from simple testing of promising drugs to long-range exploration of the internal workings of cells...
Every week dozens of new chemicals come to Sloan-Kettering from commercial laboratories, chemical houses, university scientists and medical men. Each is catalogued and given a number (to head off charges of favoritism). The more interesting ones, thought to have strong biological effects, are tried on experimental cancers planted in white mice...
...Sloan-Kettering now has 2,300 chemical agents on file, and has already tested some 1,500. Six of them proved to have a good "differential effect" against one or more types of mouse cancer. A couple of dozen had some lesser effect. According to Dr. C. Chester Stock, head of the Division of Experimental Chemotherapy, this record is by no means discouraging. As the records and experience accumulate, the scientists are learning how to predict whether a compound is worth testing. If a new one has a slight effect, one of its close relatives may prove better. And each...
...cold, air-conditioned room in Sloan-Kettering, various molds (green or white mats) are growing in flasks. The program is still young, but already one mold has been found that secretes a substance with a slight differential effect on mouse tumors. Dr. Rhoads does not even want to talk about it yet. He has no "cancer penicillin...