Word: sloan
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...elements in the mystery have been clarified, says ''Viruses and Cancer." a progress report published this week by Manhattan's Sloan-Kettering Institute for Cancer Research. In many of the cancers, including leukemias of domestic fowl and laboratory animals, a virus is an essential factor. But to say that a virus causes the cancer may be an oversimplification. The tubercle bacillus is the one essential factor in tuberculosis, but mil lions of people carry the bacillus without ever developing the disease. By analogy, researchers argue, it may be that viruses, or viruslike particles of whatever origin...
...Virus. Most baffling of all are the disappearing tactics of viruses involved in cancer. In one rabbit tumor, the virus cannot be detected in new, dividing cells, but is readily found in old cells where it has already done its damage. This seems to be a case, says the Sloan-Kettering report, of "the more active, the less evident." And it is the opposite of the situation in most viral infectious diseases, in which the virus abounds and is easily detectable as the fever approaches its climax, because infected cells are then mass-producing new virus particles...
From Plant to Man. It may be, according to Sloan-Kettering's Director Frank L. Horsfall Jr., that there are no special cancer-inducing viruses, but that in the appropriate host and in the appropriate circumstances perhaps any virus can invade the chromosomes of a cell and start the process of abnormal reproduction which we call cancer. A bit of evidence in support of this view came from Sweden's famed Geneticist Albert Levan. He has found breaks or changes in the chromosomes of children recover ing from measles. Though he still has no proof that such changes...
...heredity are, essentially, chains of DNA. When one of these vital molecules in an animal cell is altered by radiation, chemicals, or in any other way, the result may be the aberrant growth that is called cancer-which is why Dr. Wilkins is now visiting at Manhattan's Sloan-Kettering Institute for Cancer Research. Since abnormal or defective DNA molecules may cause other innate defects or disease, pioneers on today's frontiers of biochemistry and molecular medicine hope some day to reverse some human disorders by supplying tailor-made, corrective...
...their superficial differences, Dr. Dalldorf notes, the diseases have two important factors in common. The tumor cells are of the same type, and both diseases can be slowed down, or arrested for a year or two, by the same radiation and drug treatment. (Sloan-Kettering medical teams have gone to Kenya and treated many patients there.) So, suggests Dr. Dalldorf, the lymphatic cancers of children, in Africa and elsewhere, may be two sides of the same coin...