Word: sodded
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Klein cautioned that a large amount of research still lies ahead. SOD is just one player, albert "a bigger piece than we've ever had before," she said, but scientists are still searching for other altered genes responsible for cases of familial ALS not present in the current sample...
...SOD is responsible for mopping up dangerous free radicals, in this case negatively charged oxygen molecules called "superoxides," which if left unchecked may lead to cell death. A similar mechanism, involving a different set of free radicals, has been implicated in Parkinson's disease...
...finding suggests that if patients' supplies of SOD can be replenished by treatment with either SOD itself or a similar protein, there may be hope for a cure...
Brown said the research team will next look at three areas: analyzing SOD activity levels in affected patients, testing for free radical damage in patients and searching for drugs to eliminate free radicals...
...phone interview yesterday, Irwin Fridovich, a professor of bio chemistry at Duke University Medical Center, proposed several possible explanations for the increased susceptibility of neurons to decreased SOD levels in ALS patients...