Word: soiling
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Other companies are starting to look for fresh new antimicrobial agents. Cubist, in Cambridge, Mass., has an injectable form of one such agent--daptomycin--in late-stage clinical trials. Like tetracycline, it was derived from filamentous bacteria that dwell in both soil and water. But daptomycin does not work as tetracycline does by inhibiting cellular metabolism. Rather, it disrupts the conformation of the bacterium's cell membrane, more like penicillin. The way daptomycin does this appears to be unique; in other words, the resistance that disease-causing bacteria have developed to penicillin should not readily transfer to daptomycin...
...broken out almost daily between troops of the two nations. The conflict that finally erupted last week along the 1,300-mile (2,100-km) frontier was plainly big enough to raise the specter of a major conflagration on the subcontinent. The presence of Indian troops on Pakistan's soil escalated the dispute to the point where full-scale war could erupt at any moment ... India's power is far superior to Pakistan ('s). Its forces (980,000) outnumber Pakistan's (392,000) by more than 2 to 1; its air and naval capacity is also rated superior. If India...
Brown is not alone. Like the wagon-train homesteaders who traveled west only to straggle back to civilization when their crops didn't grow in the thin soil, the pioneers behind Inside.com--magazine veterans all--and a number of similar websites have seen the future, paused, reflected and decided to trek back to the past. Along with [Inside], new magazines such as Space Illustrated, Nerve, Travelocity and Expedia Travels have morphed from their cyber origins. What happened...
...Technological developments are a further hallmark of this past millennium. We have developed the three-field system, cultivating great fields of legumes to replenish the soil and increase our food supply. We have created the heavy iron plow, which can bite through the heavy earth of Northern Europe. We have even unleashed the mighty power of the horse, with a new stirrup for shock combat and a collar that enables horses to pull heavy weights without choking them to death...
...less bound by convention. Chardonnay, pinot noir and pinot meunier, for example, are the usual grapes found in champagne; L. Aubry uses the obscure grapes fromenteau, arbanne and petit meslier for some of its champagnes. Fleury Pere & Fils adopts organic and biodynamic growing methods, which it claims open "the soil and vines to cosmic influences...