Word: somatostatin
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Dates: during 1977-1977
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...insulin. In the work announced last week, Microbiologist Herbert Boyer of the University of California, San Francisco, along with Biochemist Arthur Riggs of the City of Hope Medical Center near Los Angeles and Physiologist Wylie Vale of the Salk Institute in San Diego synthesized copies of the gene for somatostatin, a hormone in the brains of mammals that inhibits the secretion of pituitary growth hormone. Then they chemically inserted the genes into the DNA of E. coli bacteria, which multiplied and began manufacturing somatostatin...
...researchers who first isolated somatostatin needed nearly half a million sheep brains to produce 5 mg. (.00018 oz.) of the substance. Using their recombinant DNA technique, the California researchers required only 2 gal. of bacterial culture to obtain the same amount...
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