Word: sorbitol
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Dates: during 1990-1990
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Diabetic complications have also been linked to elevated levels of sorbitol, a sugary alcohol. Even in the absence of insulin, certain cells, such as those in the lens of the eye, continue to absorb glucose. But without insulin, glucose cannot be processed in the usual way; the cell instead converts it to sorbitol. The abnormal accumulation of sorbitol causes cell membranes to swell and leak. It also interferes with vital biochemical processes...