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...nearly 90% of adults have been exposed to the herpes simplex virus-1 (HSV-1), which causes cold sores. People are usually infected as children, but many never have symptoms. For those who do, however, cold sores are a painful and permanent nuisance, always erupting in the same location, at the original site of infection on the lips or mouth. Once HSV-1 enters the body it hunkers down for life, most of the time hiding dormant in the cranial nerves near the spine. The virus can be triggered by outside stress, such as exposure to sunlight, a fever...

Author: /time Magazine | Title: A Cure for Cold Sores? | 7/2/2008 | See Source »

...that it was the microRNA that blocked production of the protein that activates HSV-1. "So if there was a sufficient supply of microRNA, then the virus stayed latent," Cullen says. "But under a high level of stress, the microRNA's blocking mechanisms break down, thus triggering a cold sore." The study, funded by the National Institutes of Health, will be published in the journal Nature this week...

Author: /time Magazine | Title: A Cure for Cold Sores? | 7/2/2008 | See Source »

Understanding how to override the microRNA could allow scientists to activate the virus and then kill it using acyclovir. "Once the virus sticks its head up over the fence, you whack it off for good," Cullen says. "Yes, the person has to have one last cold sore, but it'd be worth it to most people to cure them forever...

Author: /time Magazine | Title: A Cure for Cold Sores? | 7/2/2008 | See Source »

...while it is odd for public disaffection to coalesce around farm owners, an anti-Cristina rally organized by the farmers a week ago in the city of Rosario drew between 200,000 and 300,000 people. That kind of turnout hit a sore spot with the presidential couple. Former President Kirchner tried to denigrate it by comparing it to the rallies against Juan Peron in 1945 - which, though large in number, failed to prevent Peron's rise to power along with his wife Eva, who is still widely revered in Argentina. The farmers scoffed Kirchner's belittling. "Make no mistake...

Author: /time Magazine | Title: A Meltdown for Argentina's Hillary | 6/2/2008 | See Source »

...Obama’s chances in the fall election. Their attacks on one another amount to doing McCain’s dirty work for him.But that battle will soon be over and such divisions will heal quickly formost Democrats. While the folks on the losing side will be sore, most will quickly rally to the nominee. They’ll get over it and for good reason. If Hillary Clinton loses, her supporters will be bitter but will wind up for Obama because whatever differences exist between Hillary and Barack, they are nothing compared with the differences between a Republican...

Author: By David Yepsen | Title: If It Ain’t Broke... | 4/28/2008 | See Source »

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