Word: souza
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Currently, most anti-HIV drugs target individual proteins, and are given in combination as a cocktail. However, according to D’Souza, HIV is mutating and building up resistance to the cocktail. By studying the RNA-protein complex, which is crucial to the virus’ survival, D’Souza aims to sophisticate the current approach to AIDS treatment...
...next three to four years, D’Souza says she should be close to solving the structure of the RNA-protein complex, which is, according to her, “probably the most difficult part...
...next step would be to conduct drug-binding experiments. According to D’Souza, an effective drug would target the interaction between RNA and the reverse transcriptase protein, unlike current drugs which target just the protein...
...Souza has been given a three-year, $300,000 grant from the Damon Runyon Cancer Research Foundation—awarded to five outstanding researchers during the initial years of their first faculty position...
...Souza says she would not be able to tear herself away from virology even if she were not doing HIV research, because of her love for microbes...