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...known as mGluR5 receptors (the Glu is for glutamate, a key signaling agent in the brain). They reasoned that it would be possible to correct the excesses of Fragile X by blocking these receptors, which act as accelerators of protein production. To test this idea, the researchers produced a special breed of mice that had the Fragile X trait but only half the normal number of mGluR5 receptors. The result, explains Bear: "We were able to correct the excesses [of Fragile X], taking our foot off the accelerator...

Author: /time Magazine | Title: A New Approach to Correcting Autism | 12/19/2007 | See Source »

...Hollywood should realize by now that it can't use every war as an opportunity to make money. The reality is that movies are still perceived as a source of sheer entertainment; moviegoers go to the theaters to laugh, cry or just be impressed by the cool special effects. You don't really get that amusement when you're watching a movie that is all about how your government made the wrong choices and your countrymen are dying as a result. Even if the motive of a movie is to teach a moral lesson, it's not easy to stick...

Author: /time Magazine | Title: Inbox | 12/19/2007 | See Source »

...Zuma, to be sure, is hardly an ideal leader. Mbeki sacked him as Deputy President in 2005 after his financial adviser was convicted of corruption over an arms deal with a French company, and last week the Directorate of Special Operations filed papers in the Constitutional Court expanding similar charges against Zuma himself. And in 2006, he was in court again, acquitted on a rape charge, although his testimony nonetheless revealed questionable attitudes on sex, including an admission that he had unprotected sex with a woman he knew to be HIV positive...

Author: /time Magazine | Title: South Africa's Mbeki Repudiated | 12/18/2007 | See Source »

...such, and not as excuses to exploit well-intentioned schools to the full extent of the law. Yet, the problem cannot be blamed on unreasonable parents alone. The Adrian and Warren cases should have taught school administrators to be more alert in general, and take additional precautions with special-needs children in particular. Instead, many have chosen an easier path—eliminate all potential for liability—that is also a gross overreaction. Eliminating recess will not fix the real problems such as bullying, but instead deprives children of the opportunity to exercise their imagination, compete, and risk...

Author: By The Crimson Staff | Title: Rescue Recess Indeed | 12/17/2007 | See Source »

...story, and involves issues of sovereignty and human rights," notes Robert Dujarric, director of Temple University's Institute of Contemporary Japanese Studies. "The issue has taken on a life of its own." The government has called the kidnappings "acts of terrorism"; former Prime Minister Shinzo Abe set up a special task force on the issue last year. Families of the victims have become national celebrities, and make regular media appearances not only to campaign for their cause but also to speak out on politics and nuclear disarmament. Hatsuhisa Takashima, special assistant to the Minister for Foreign Affairs, says a recent...

Author: /time Magazine | Title: Japan's Problem With N. Korea Talks | 12/17/2007 | See Source »

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