Word: sperm
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Dates: during 2000-2009
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When CatSper is not present, sperm become lethargic and may be unable to enter the crucial “hyperactivation” stage that allows it to break through the membrane protecting...
Clapham says he was looking for new ion channels when he discovered one that happened to be present only in sperm...
Unlike Clapham, who is in interested primarily in ion channels, Garbers’ lab has done work on the way that sperm gets signals from its environment...
Clapham’s group discovered that CatSper is found only in the part of the sperm cell that connects to the sperm’s tail, or flagellum. This part contains the molecular machinery that allows the sperm to wave the flagellum and move forward...
...Since the channel is only in sperm, it is likely that the compound would affect no other cells in the body,” says Garbers...