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...test, described by Medical Researchers David Blake and Stephen Spielberg, white blood cells from humans are mixed with liver tissue from humans or other species plus the drug under study. Then the preparation is examined to see if enzymes in the liver have metabolized the drug into a substance that kills white cells. The researchers believe that such toxic metabolites may be responsible for birth defects; some of their studies suggest that thalidomide works that way. The new test, for instance, shows that thalidomide does form a toxic metabolite, areneoxide, in the presence of liver tissue from rabbits, monkeys...

Author: /time Magazine | Title: Medicine: Helping Babies in the Womb | 5/25/1981 | See Source »

...worth more than $100 million. He is building a model-village production plant-a sort of Disney World for cineastes-in Northern California's Marin County. He has seven more Star Wars movies in mind. And he has just produced an adventure film by another strong director: Spielberg's Raiders of the Lost Ark. Spielberg is proud that their picture was completed under schedule and within the budget: $19 million. "Lucas was to me what David O. Selznick was to his directors on Gone With the Wind. I respect his comments totally. Raiders proved that two people...

Author: /time Magazine | Title: Cinema: The New Hollywood: Dead or Alive? | 3/30/1981 | See Source »

...Lucas has a bank called Star Wars," notes Spielberg, 33. "Coppola doesn't have a bank-only courage and fortitude. Chutzpah too: his Zoetrope Studios is preparing more than a dozen challenging projects, despite the fact that Coppola nearly went bankrupt just a month ago. The minimogul, who drives a mini-limo, a customized black Volkswagen Rabbit with dark tinted windows, admits that it is hard to keep one eye on the artistic horizon and the other on the bottom line. "Film makers are not necessarily good administrators. And the concept of the studio is vitally important...

Author: /time Magazine | Title: Cinema: The New Hollywood: Dead or Alive? | 3/30/1981 | See Source »

...qualities much of the filmmaking world was exploring with a vengeance The Truffaut of The 400 Blows gave way to the Truffaut of The Man Who Loved Women and Day for Night. He treated even his most repellent characters with extraordinary affection. When Trauffaut took a role in Steven Spielberg's Close Encounters, it was, fittingly enough, that of the starry-eyed scientist who looked to the sky with an unbridled, childlike innocence. These hyper-intelligent jellyfish aliens glided out of the Mother Ship, and there was the benevolent Truffaut, signalling good will and smiling his beatific smile. Jean...

Author: By Thomas Hines, | Title: Truffaut's Diffidence | 3/2/1981 | See Source »

Traditionally, artists begin their careers by imitating their masters and gradually developing or refining a style that in the happiest cases becomes unique. In recent American films, though, the process has been reversed. Hot young directors like Steven Spielberg and John Landis have exercised their talent on elaborate homages to the Three Stooges. Brian De Palma has taken up permanent residence as a grinning caretaker of the Hitchcock reliquary. Paul Mazursky has stared into his navel and found François Truffaut. And Woody Allen, whose films find their strength in reflections on his life and the lives...

Author: /time Magazine | Title: Cinema: A Comic Master Goes for Baroque | 9/29/1980 | See Source »

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