Word: spinal
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...article on Dara Torres. As a 40-year-old father of three young ones, I have long taken pride in my training and strength. I invested a lot of time in trail-running and martial arts. However, this past November I underwent neurosurgery to remove a tumor from my spinal cord. I now need a cane to walk and have lost dexterity in my right arm. Not only will women be cheering for Dara, but us "older" guys will be stomping our canes for her as well. Robert Zuni, Martinez, California...
...Eggan's group has successfully turned stem cells into motor neurons, the cells that connect the spinal cord to the body's muscles and which degenerate in ALS. But researchers have not been able to prove that these cells will be clinically useful - that is, whether the new nerve cells will work as well as healthy ones in the spinal cord of a patient. Testing the viability of cells made from iPS stem cells is still a long way off, mostly because iPS requires the use of viruses to deliver the time-reversing genes into adult cells - that works...
...diseased cells, Henderson says, they may very well develop signs of the disease in culture, allowing researchers to watch ALS unfold before they eyes. "Our lack of understanding of the disease process is preventing us from developing more efficient cures," says Henderson. "Because the disease is happening in the spinal cord, we don't have access to living samples of neurons undergoing the disease process. But now we have in the culture dish the very cells affected by the disease...
...theory about the cause of ALS is that motor nerves die after exposure to a toxic compound released by other nerve cells in the spinal cord. The Harvard and Columbia groups are hoping to test that idea in the lab: if the cells in culture release the same agent, then finding drug compounds that block the damaging effects of the toxin could preserve neurons and hold off the paralyzing effects of the disease...
...gonna come out in November that would be the 25th anniversary of the movie. We've been talking about some kind of concert tour. We really love to get together. We make each other laugh still. And we love playing music, so why wouldn't we do that? The Spinal Tap business has been a - what do they say on the business shows? - a declining asset for some time in terms of us. Somebody's making money off of Spinal Tap, but not us. So we thought the 25th anniversary would be a good time to turn that around...