Word: spinal
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...most of them have never heard of Wise Young. If they did meet him, however, they'd want to shake his hand--and the remarkable thing about that would be the simple fact that so many of them could. All the people Young has helped were victims of spinal injuries, and they owe much of the mobility they have today to his landmark work...
Young, 51, head of the W.M. Keck Center for Collaborative Neuroscience at Rutgers University in New Brunswick, N.J., was born on New Year's Day at the precise midpoint of the 20th century. Back then, the thinking about spinal-cord injury was straightforward: When a cord is damaged, it's damaged. There's nothing that can be done after an injury to restore the function that was so suddenly lost...
...medical student at Stanford University and a neurosurgeon at New York University Medical Center, Young never had much reason to question that received wisdom, but in 1980 he began to have his doubts. Spinal cords, he knew, experience progressive damage after they're injured, including swelling and inflammation, which may worsen the condition of the already damaged tissue. If that secondary insult could be relieved with drugs, might some function be preserved...
...global revolution, actually. More than 50,000 people around the world suffer spinal injuries each year, and these days, methylprednisolone is the standard treatment in the U.S. and many other countries. But Young is still not satisfied. The drug is an elixir for people who are newly injured, but the relief it offers is only partial, and many spinal-injury victims were hurt before it became available. Young's dream is to help those people too--to restore function already lost--and to that end he is studying drugs and growth factors that could improve conduction in damaged nerves...
...cure for spinal injury is going to be a combination of therapies," Young says. "It's the most collaborative field I know." Perhaps. But increasingly it seems that if the collaborators had a field general, his name would be Wise Young...