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Some scientists believe that the neurotransmitters are just links in a chain of reactions and that the real master molecules of mood reside higher up in that chain. One leading candidate: a substance called corticotropin- releasing hormone, or crh, which is pumped directly into the spinal fluid and thus bathes the entire brain at once. Discovered in 1981 by researchers studying the biochemistry of stress, crh is known to promote vigilance and decrease interest in food and sex when administered in small doses. In higher doses, it triggers anxiety. When Philip Gold, chief of the clinical neuroendocrinology branch...

Author: /time Magazine | Title: Depression the Growing Role of Drug Therapies | 7/6/1992 | See Source »

...certainty: on the night of March 10, 1981, in the town of Grundy, a young woman named Wanda Fay McCoy was raped, stabbed twice in the chest and slashed across the neck with such force that the gash, 4 in. wide and 2 in. deep, cut almost to her spinal cord. When her husband Brad returned home, he discovered Wanda lying on the floor in a warm pool of blood. Her cable-knit sweater was hiked up around her neck and her indigo underpants shoved down around her left foot...

Author: /time Magazine | Title: Roger Keith Coleman: Must This Man Die? | 5/18/1992 | See Source »

...lead to tumors in certain animals, including humans. The rare tumors associated with the virus usually appear before two years of age in humans, and doctors often have difficulty treating them because they lie deep within the brain, in an area known as the choriod plexus, which manufactures cerebro-spinal fluid...

Author: By Ivan Oransky, | Title: RESEARCH BRIEFS | 4/15/1992 | See Source »

...something magic about them," says California neurosurgeon Robert Iacono. In experiments with rats, | mice and monkeys, scientists have discovered that fetal cells are effective in treating a wide range of stubborn conditions. Transplanted cells have cured diabetes and restored some sight in animals. The cells have repaired some spinal-cord injuries, allowing injured rats to run at normal speed. Implants in the brain have improved memory and learning. The work has led scientists to speculate that the cells can be used to treat epilepsy, combat leukemia and stop such degenerative diseases as Huntington's chorea and Alzheimer...

Author: /time Magazine | Title: When Abortions Save Lives | 4/6/1992 | See Source »

...startling discovery, reported in Nature by an international trio of research teams, marks only the third time such a genetic phenomenon has been found. Last year researchers revealed a similar process in two much rarer inherited diseases: fragile X syndrome, a form of mental retardation; and spinal and bulbar muscular atrophy, a wasting disease...

Author: /time Magazine | Title: The Generational Saga of The Vicious Gene | 2/17/1992 | See Source »

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