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Subjecting these cells from Marilyn's spleen to the sort of genetic wizardry unavailable during the animal's lifetime, Hahn and her colleagues, including Feng Gao, husband George Shaw and Paul Sharp, set about amplifying, sequencing and analyzing Marilyn's virus. Except in the rarest cases, chimps like the sooty mangabeys never show AIDS-like symptoms. Even so, when the researchers compared the viral DNA with the three known types of SIV (simian immunodeficiency virus), they found it had a substantially different genetic makeup. And when they compared Marilyn's genetic makeup with that of other chimps, they determined that...

Author: /time Magazine | Title: The First Chimpanzee | 2/8/1999 | See Source »

...Fish, samurai, world traveller, Lensky was named for the romantic poet of Pushkin's "Eugene Onegin" who is killed in a duel with the novel's title character. Lensky himself never led the romantic life that his namesake fancy, but he did exhibit the feeling of modish spleen of the 19th-century aristocratic like the characters in Pushkin's novel. Lensky could always be found languoring in his bowl, not doing much of anything, a bored, flat expression on his face...

Author: By Marshall I. Lewy, | Title: From Abroad | 2/26/1998 | See Source »

When Casey collapsed on Christmas Eve two years ago, Betty Lieu rushed him to the hospital, where doctors found his spleen was cancerous and removed it. The prognosis was grim. Even with chemotherapy, Casey would have only a few months to live. Desperate, Lieu, a retired legal secretary in Los Angeles, decided instead to take a chance on a holistic healer who offered to boost Casey's immune system with herbs. Much to Lieu's delight, Casey gained back the weight and energy he had lost, and his coat is once again shiny and full...

Author: /time Magazine | Title: ST. BERNARD'S WORT | 11/3/1997 | See Source »

...disease is transmitted by the bite of a sand fly that is about one-tenth of an inch long and is ubiquitous in certain woodlands. Once inside the body, the kala-azar protozoan invades and weakens the immune system, causing fever, weight loss, anemia and enlargement of the spleen. If the disease is untreated, a secondary infection, such as pneumonia or malaria, usually brings painful death...

Author: /time Magazine | Title: RESCUE IN SUDAN | 10/1/1997 | See Source »

...19th century, kala-azar ravaged much of eastern India, where it earned its name--Hindi for "black sickness." In 1900 a British physician, Dr. William Boog Leishman, developed a stain to detect the parasite with a microscope, and Dr. Charles Donovan demonstrated that specimens could be extracted from the spleen. In their honor, the deadly parasite is called Leishmania donovani. Variants of kala-azar are found in southern Europe and South America. A complex treatment involving daily injections of a potentially toxic, antimony-based compound (as in the drug Pentostam) has been available for a half-century...

Author: /time Magazine | Title: RESCUE IN SUDAN | 10/1/1997 | See Source »

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