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...team of Harvard Medical School (HMS) researchers, led by Professor Timothy A. Springer and Research Fellow Conrad Bleul, announced yesterday that they have discovered and isolated a secondary strain of HIV, called the T-tropic strain...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...Springer, the Latham Professor of Pathology, and Bleul, a fellow in pathology at the Center for Blood Research, found that the T-tropic strain attacks a different portion of the immune system than does an earlier strain of HIV, called M-tropic strain...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...Springer and Bleul discovered that once partially ingested into the immune system, the two strains complete their invasion through the use of two different chemokine co-receptors. Chemokines are chemicals which signal immune cells to an infection...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...Springer and Bleul discovered that there are separate co-receptors for the strains; M-tropic goes through a [different] set of doors than T-tropic. The critical point of the research is that there are two different doors," Landau said...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...Before this was all really phenomenology. Nobody really had any way of relating this to a basic mechanism, a molecule, a co-receptor," Springer said in a press release...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

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