Word: squibbs
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...American Heart Association. Just two weeks ago, a study in the British Medical Journal concluded that statins could reduce the risk of dying from a heart attack 30% even among those with normal cholesterol levels and no sign of cardiovascular disease. Pharmaceutical giants Merck and Bristol-Myers Squibb have gone so far as to petition the Food and Drug Administration to allow consumers to buy some low-dose statins over the counter, without first having to obtain a physician's prescription (more on that below...
...small amounts of the same active ingredient found in lovastatin (Mevacor). The FDA tried to ban the supplement's sale in the U.S., but the action has become the subject of a lengthy court process. The controversy hasn't stopped Merck, which manufactures Mevacor and Zocor, and Bristol-Myers Squibb, which produces Pravachol, from arguing that they should be allowed to sell their pharmaceutical-grade products at similarly low doses to the general public...
HAIR TODAY...With partner Bristol-Myers Squibb, razor titan Gillette is sharpening another weapon against hair: Vaniqa (VAN-i-ka), a prescription cream recently approved by the FDA that zaps unwanted facial hair on women. The impact can be dramatic, but possible side effects include rashes, redness and acne. And don't toss that SensorExcel just yet. Vaniqa doesn't entirely replace regular fuzz control...
Merck and Bristol-Myers Squibb say they are pushing for OTC status for their products to make them more widely and cheaply available. But analysts note that Merck's patent on Mevacor expires next year. And while Bristol-Myers Squibb's patent on Pravachol runs to 2005, generic versions of Mevacor will surely cut into Pravachol's sales, justifying Bristol-Myers' push for OTC too. An added benefit: a switch could give the maker exclusive selling rights on the drug for three more years. That's why medicines like the hair-loss treatment Rogaine (owned by Pharmacia Corp...
...paper, and now we had the scissors," says Selkoe. If he is right, one of those scissors, gamma secretase, may actually be the presenilin-1 protein. Whatever the true identity of gamma secretase turns out to be, pharmaceutical companies are rushing to develop drugs that block it. Bristol-Myers Squibb has already started safety tests of one such compound and hopes to expand its study soon...