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Developed by Bristol-Myers Squibb, DDI resembles AZT in that it interferes with replication of the AIDS virus. Whether it will extend the life of patients remains unknown, but it has been shown to boost levels of disease- fighting T cells. Last week's approval, granted with unusual speed, will enable doctors to prescribe the drug to those who cannot tolerate AZT -- about half of AIDS patients...
Late last week, however, the FDA bucked its own bureaucratic tradition when one of its advisory committees recommended that a similar drug made by Bristol-Myers Squibb, called DDI, or dideoxyinosine, be put on the market even though it has not undergone the agency's standard testing. While the decision heartened many AIDS organizations, some desperate patients have resorted to an immediate alternative: black-market DDC. Underground AIDS groups are buying the drug in bulk directly from chemical companies, which manufacture it for use in laboratory experiments. The clandestine suppliers then weigh out and package the counterfeit pills and sell...
...Pacific Coast's forests are teeming with hidden drugs, including the legal kind. Last week the Agriculture Department decided to allow the pharmaceutical company Bristol-Myers Squibb to cut down 38,000 Pacific yew trees for one such substance. The bark of the yew tree is the sole source for a drug called taxol, a promising treatment for breast and ovarian cancer. Despite concerns over the impact of the yew harvest, most environmental groups support the agreement because it specifies that Bristol-Myers will pay for Forest Service research into conservation and management of the yews...
...that the agency's analysis was not yet complete and that in any case the 4-in-10,000 figure greatly overstated the risk. "We don't know where those numbers came from," she said. Still, the FDA applauded a decision by the implants' manufacturer, Surgitek, a Bristol-Myers Squibb subsidiary, to halt immediately the worldwide distribution of the products until the investigation was completed...
...claim that the leaders of the $1.5 billion formula business have unfairly boosted their prices 150% during the 1980s. Last week the state of Florida filed a lawsuit in federal court against the top U.S. formula makers: Abbott Laboratories (maker of Similac), American Home Products (Nursoy) and Bristol-Myers Squibb (Enfamil). The civil suit accuses the companies of fixing and inflating formula prices...