Word: statin
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...Ridker said that there was a small increase in diabetes for patients given the statin in the study. But, he said, “almost all” of the diabetes occurred among patients with “impaired fasting glucose,” or those who were “already heading toward diabetes...
...ages 50 and older and women ages 60 and older, who had high levels of C-reactive protein (CRP) but normal cholesterol levels and no history of heart disease. Half the participants were given rosuvastatin (Crestor), and half were given a placebo daily for just under two years. The statin group reduced their CRP levels by 37%; their LDL, or bad cholesterol, levels dropped 50% to about 55 mg/dL. Among the 8,901 statin-takers, 31 suffered a heart attack and 33 suffered a stroke. When compared with the placebo group, those figures translated to a 54% lower risk...
Although JUPITER (Justification for the Use of Statins in the Prevention: an Intervention Trial Evaluating Rosuvastatin) was designed to study inflammation, its findings also underscore the risk of high cholesterol. The study's statin group clearly benefited from reducing CRP, but they had also simultaneously lowered their LDL levels to nearly 50% below the government-prescribed target of 100 mg/dL. Experts say the JUPITER results may prompt serious rethinking of the current guidelines - an issue that health officials have already been debating in recent years. "I would not be surprised if, given these results, we determined that normal LDL should...
...study suggests that screening all patients for CRP (a $10 test) as well as for cholesterol and blood pressure would not be unwise, or perhaps the test should be used for patients with indeterminate heart-disease risk, who may derive benefit from taking a statin. Longer-term trials are still needed, however, to show whether the benefits of statins outweigh their potential side effects - the drugs are relatively benign, but they are known in rare cases to cause debilitating side effects such as muscle weakness (which forced Bayer to pull its version off the market in 2001). There...
...over, but squeezes in risk information only once and just after the halfway mark. You won't see it on TV anymore - the drug maker pulled the ad in January after releasing results of a two-year trial that showed Vytorin was no better than a cheaper generic statin drug at preventing heart disease - but you can watch our dissection of it below...