Word: statin
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...trial of the cholesterol-lowering statin drug Lipitor last March found that high doses lowered patients' levels of LDL (the "bad" cholesterol) and also reduced their heart-attack risk. That's why the results of a new study on similarly high doses of the statin Zocor are so disappointing. In the 4,500patient study, published online by the Journal of the American Medical Association, patients taking high doses of Zocor fared no better than a low-dose group in terms of heart-attack risk, despite low LDL levels. Why? Perhaps because Lipitor works not just by lowering cholesterol but also...
...recommendations are likely to sharply increase the use of statin drugs. It's almost impossible to achieve such low LDL levels without the cholesterol-cutting medications, and last week consumer groups complained that the NCEP committee failed to disclose that at least six of its nine members had financial ties to companies that make them. But even the NCEP says the best ways to lower cholesterol are to get more exercise, eat less saturated and trans fats, and maintain a healthy weight. "Patients often think, Since I'm taking a statin, I'm protected," says Dr. Eric Topol, a cardiologist...
...Statin drugs have helped millions of heart patients lower their cholesterol level--and may have helped in other ways as well. A study last week showed that long-term statin use may lower the risk of glaucoma; another suggested that the drugs may offer relief from rheumatoid arthritis. That's the good news. The bad news is that statins don't work as well for everyone. A big study published in the Journal of the American Medical Association found the statin Pravachol was up to 22% less effective in patients with two common variations in one of 10 genes involved...
...worried about competition from the new, low-tax Eastern European E.U. members. But their plans to push for E.U.-wide tax harmonization are fiercely opposed in Brussels by Britain , Ireland and others. It may be a while before anyone's singing We Are the Champions. U.K. Becomes A Statin Island I n the fight against heart disease, drugmakers last week hailed a British government decision to green-light over-the-counter-sales of the cholesterol-lowering drugs known as statins, the first such approval in the world. Starting in July, Zocor - made by U.S. pharmaceutical firm Merck, but marketed...
...start badgering your doctor for a statin prescription just yet. "I would like to see more studies," says Dr. Jacque Duncan, a professor of ophthalmology at the University of California, San Francisco, who led the latest study. Statins, though remarkably safe, can trigger side effects, like severe muscle and joint pain. Long-term use of aspirin increases the risk of internal bleeding. Moreover, it isn't clear why either statins or aspirin works against AMD; the leading hypothesis is that their ability to dampen inflammatory processes in the body...