Word: statins
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Dates: during 2000-2009
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...heart disease. And although it seems logical to assume that reducing fatty deposits will translate into fewer heart attacks and deaths, that hasn't been proved. The patients in this study will have to be watched a lot longer than 18 months to find out. Meanwhile, there are more statin studies in the works, including a big one sponsored by Bristol-Myers Squibb (this one was paid for by Pfizer). Those studies could show that there's an even better statin out there. Hmm, maybe I'll wait for that...
ApoA-1 Milano eventually became the property of Esperion Therapeutics, in Ann Arbor, Mich., which persuaded Nissen to conduct the studies that led to last week's report. If the results hold up in larger trials, they could be revolutionary. Statin drugs, which lower the bad LDL cholesterol that causes plaque in the first place, reduce the risk of dying from heart disease only 30% or so. By targeting HDL as well, the risk might be halved. Says Nissen: "We're starting to talk about really limiting what this disease...
...Statins, the cholesterol-lowering wonder drugs, are getting a lot of press these days. And, to be sure, they can save lives by dramatically lowering blood levels of LDL, the "bad" cholesterol. But statin drugs are expensive and work only as long as you keep taking them. Also, they can have side effects and should not be taken by people with liver problems...
...lower your cholesterol nearly as effectively as medication. Writing in the current issue of the Journal of the American Medical Association, researchers at the University of Toronto describe an experiment that compared three different regimens: a vegetarian diet low in saturated fats; the same diet supplemented with a statin drug (in this case, lovastatin); and a fiber-rich vegetarian diet consisting of foods chosen for their known cholesterol-lowering effects (such as oats, barley, soy protein and almonds) as well as a type of margarine enriched with plant sterols (cholesterol-lowering compounds found naturally in leafy green vegetables and vegetable...
...despair. They can be lowered. In fact, the lifestyle changes and medications that doctors recommend to lower cholesterol do double duty and also reduce CRP. Avoiding fatty red meat, eating more fruits and vegetables and exercising should be the first response--if making those changes is not enough, statin drugs may help...