Word: steigbigel
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...Still, Berkley and others say that the wider range of drug options can only help vaccine makers, giving them a larger well of knowledge upon which they can draw. Yet, even as newer classes of ARVs arrive, drugs cannot be the only answer to AIDS. Already, says Dr. Roy Steigbigel of State University of New York at Stony Brook, and one of the leading investigators of Merck's isentress, volunteers have begun to develop resistance to the integrase inhibitor - a drug that hasn't even yet been approved...
...Neal Steigbigel, chief of infectious disease at Montefiore Hospital in the Bronx, thinks male-to-female transmission is bound to occur more often simply because of the mechanics of vaginal intercourse. Harvard Virologist Martin Hirsch, however, notes that herpes and syphilis appear to travel equally well in either direction between the sexes. Hirsch thinks the only reason more women have contracted the AIDS virus from men than the other way around is that many more men now have the disease. As more women become carriers, he suspects, they will infect their partners. "There is no doubt," says Dr. Margaret Fischl...
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