Word: stemness
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Dates: during 2000-2009
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...will continue to rise, thanks to panicky raids of federal coffers by policymakers trying to stem the financial crisis. President George W. Bush started the current bonanza in February by approving a $152 billion economic stimulus package. When other bailouts, including the recently passed $700 billion financial rescue plan, are counted, Washington is set to shell out some $1.5 trillion in the near term. Projections for the next fiscal year's deficit start at roughly $550 billion and go as high as $1 trillion, depending on the government's current obligations, expected further spending measures and falling tax revenues related...
...Stem the tide of foreclosures. The original Paulson plan is like a massive blood transfusion to a patient with severe internal hemorrhaging. We won't save the patient if we don't do something about the foreclosures. Even after congressional revisions, too little is being done. We need to help people stay in their homes, by converting the mortgage-interest and property-tax deductions into cashable tax credits; by reforming bankruptcy laws to allow expedited restructuring, which would bring down the value of the mortgage when the price of the house is below that of the mortgage; and even government...
HSCI co-director Douglas A. Melton and his colleagues have successfully created induced pluripotent stem (iPS) cells using a chemical that can replace two of the four potentially cancer-causing genes previously needed to reprogram adult cells into a mutable state. The findings, published Sunday on the Web site of the journal Nature Biotechnology, open another avenue for researchers hoping to create iPS cells that are safe for treating human disease...
...method late last year. Integrating these viruses into the cells' DNA causes permanent genetic manipulation, which can trigger malignant tumor growth, making them unsafe for human use. Scientists ultimately hope to clear this hurdle and treat a wide variety of human diseases by transplanting body tissues created from stem cells. Only three weeks ago, Harvard Medical School professor Konrad A. Hochedlinger and his colleagues at HSCI reported that they created mouse iPS cells using harmless adenoviruses that don’t alter the genetic makeup of the cells...
...Melton’s research is the first to demonstrate that scientists may be able to use chemicals instead of viruses and genes to reprogram adult cells into a more mutable state, a development long hoped for by stem cell researchers...