Word: steroid
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Cuernavaca, Mexico, best known as a place for eating, dancing and laughter, last week played host to a serious conference: a troop of eminent physicians, mostly from the U.S., gathered for the first International Symposium on Steroid Hormones. Attending the conference by proxy were millions of the desperately ill. The mysterious steroid hormones, all built neatly around the same four-ringed nucleus, offer promise of understanding a long list of chronic diseases...
Mexico City, which makes tons of hormones out of a poisonous root found in the lowland jungles. Syntex's leading product, pregnenolone, is a synthetic steroid widely used as a substitute for scarce cortisone in the treatment of arthritis...
Cabeza de Negro. The usual source of many promising steroid hormones is slaughterhouse products, e.g., glands. The supply is strictly limited; all the world's slaughterhouses together could not fill the present demand...
Dobriner points out that steroid identification is not a good test for early cancer. It is not sure; it takes too long, and it costs too much ($10,000 for a complete job). But he is cutting down the time and cost. As he collects more records, other startling facts are showing up. For instance, people with hypertension (high blood pressure) generally excrete a special steroid. No one knows why, but Dobriner hopes to find out. The mysterious steroids from the glandular orchestra are apparently concerned with all the changes in the body's cells. "If you want...
...unknown "anti-rheumatic substance X" might be a hormone from the adrenal glands. In 1946, with the help of Merck & Co. chemists, they developed a compound from the adrenal glands of cattle. It was called Compound E (full name: 17-hydroxy-11-de-hydrocorticosterone). Compound E belongs to the steroid group of body chemicals. So do the sex hormones (a link with relief during pregnancy) and some bile products of the liver (a link with jaundice). Compound E was obtained later from an element of bile. Seven months ago Mayo's began treating human patients...