Word: steroids
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Dates: during 1950-1959
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Robert B. Woodward, professor of Chemistry, will read a paper before The Chemical Society of London tonight announcing that he and a research team of four men have completed the first total synthesis of a complete steroid...
Cuernavaca, Mexico, best known as a place for eating, dancing and laughter, last week played host to a serious conference: a troop of eminent physicians, mostly from the U.S., gathered for the first International Symposium on Steroid Hormones. Attending the conference by proxy were millions of the desperately ill. The mysterious steroid hormones, all built neatly around the same four-ringed nucleus, offer promise of understanding a long list of chronic diseases...
Mexico City, which makes tons of hormones out of a poisonous root found in the lowland jungles. Syntex's leading product, pregnenolone, is a synthetic steroid widely used as a substitute for scarce cortisone in the treatment of arthritis...
Cabeza de Negro. The usual source of many promising steroid hormones is slaughterhouse products, e.g., glands. The supply is strictly limited; all the world's slaughterhouses together could not fill the present demand...
Syntex uses a vegetable raw material, cabeza de negro (niggerhead), a Mexican wild vine whose lumpy, woody root contains a soapy-feeling compound called sapogenin. In its raw state sapogenin is not a hormone, but its molecule contains the basic steroid nucleus.*This can be separated by a simple process and built up chemically into any number of hormonelike compounds...