Word: stiffer
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...heart failure, in which the cardiac muscle becomes weakened and can no longer pump blood efficiently. Investigators are currently studying a group of specialized hormones that are released whenever the heart muscle falters. Some of these hormones help restore the heart's vigor while others, paradoxically, make the muscle stiffer and more difficult to contract. The goal is to figure out a way to boost the levels of the beneficial hormones while lowering those that make the weakened heart's job more difficult...
Frank also attacked the system of drug-enforcement as racially-biased, saying that the mandatory minimum guidelines had stiffer sentences for drugs often, according to Frank, used by minorities...
...These days, the penalties are stiffer, and most states adhere to an agreement providing reciprocity: A license suspension in Maine, for example, would carry over into Texas...
Indeed, as patients clamor for every new drug that's advertised on TV and every test they learn about on the Net, the price of medicine is getting stiffer, jumping an estimated 10% this year. For the moment, Aetna and others are passing along that added expense to employers and consumers, one of the primary reasons the sector has rebounded a bit on Wall Street. But as Merrill Lynch senior analyst Roberta Goodman points out, "that's like running up the down escalator--the trend is against you." And even though Donaldson produced better-than-expected earnings of $184 million...
...that point, O'Brien's ratings were up despite stiffer competition, and viewers and critics had warmed to his go-for-broke style, annoying laugh and unruly hair...