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Word: strained (lookup in dictionary) (lookup stats)
Dates: during 1990-1999
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...coming from another world. It was engineered by scientists at Princeton, M.I.T. and Washington University, who cleverly altered its DNA--or, more precisely, that of its genetic forebears--in ways that changed the reactions between neurons deep within its tiny cranium. The result, say its creators, is a strain of mouse (which they nicknamed "Doogie," after the precocious lead character of the old TV show Doogie Howser, M.D.) that is smarter than his dim-witted cousins. Not only that, the scientists wrote in last week's issue of the journal Nature, "our results suggest that the genetic enhancement of mental...

Author: /time Magazine | Title: Smart Genes? | 9/13/1999 | See Source »

...animals (which happen to be good at learning), less active in adults (who aren't), and is found mostly in the forebrain and hippocampus (where explicit, long-term memories are formed). The researchers spliced the gene that creates NR2B into the DNA of ordinary mouse embryos to create the strain they called Doogie. Then they ran the mice through a series of standardized tests--sort of a rodent sat. In one, the mice were given a paw shock while in a box; after a few rounds, they showed signs of fear from just being in the box, having learned that...

Author: /time Magazine | Title: Smart Genes? | 9/13/1999 | See Source »

Samuel Sheinbein is one hot potato latke. First, the Maryland teenager put a strain on U.S.-Israel relations by fleeing a murder charge back home and taking advantage of an obscure section of Israeli law to evade extradition. Now, the New York Times reports, he?s accepted a plea bargain with Israeli prosecutors that will see him serve a 24-year sentence that could have him out on parole in 14 years. While that might be a stiff penalty for an 18-year-old in Israel?s courts, it pales before the life-without-parole sentence he faced in Maryland...

Author: /time Magazine | Title: Teen's Israel Plea Deal Won't Impress U.S. | 8/25/1999 | See Source »

...could be the first crack in that dam - one probably caused by the overuse of the wonder drug. According to figures released Thursday by the Centers for Disease Control, more than 200 people in Minnesota and North Dakota have become ill - and four have died - after contracting a lethal strain of the staph germ known as staphylococcus aureus. Most disturbingly, the mutated germ apparently came not from the hothouse environment of hospitals - where it is common but considered manageable - but from somewhere outside...

Author: /time Magazine | Title: Deadly Outbreak Fuels Fears About Antibiotics | 8/20/1999 | See Source »

...incredible that you did not discuss the effect of mental stress on one's health. Getting rid of tension and strain can play a role in reducing or controlling cardiac disease. You cannot expect that diet and exercise alone will protect you. DAVID W. HOWARD Bahia, Brazil...

Author: /time Magazine | Title: Letters: Aug. 9, 1999 | 8/9/1999 | See Source »

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