Word: streptomycin
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...Selman A. Waksman, 60, discoverer of streptomycin and neomycin (TIME, April 4), has dreamed for years of better facilities for hunting new antibiotics and for teaching others to join in the search. Last week streptomycin and the generosity of Scientist Waksman brought the dream near reality. Rutgers University announced that Dr. Waksman had turned over his patent rights to the Rutgers Research and Endowment Foundation...
...cones (the part used in making beer) produced two promising antibiotics, said Dr. W. D. Maclay, of the Western Regional Research Laboratory in Albany, Calif. One, called "lupulon," seemed to be as effective as streptomycin against tuberculosis in mice; its hop-twin, "humulon," worked in the test tube against...
Last week Scientist Waksman (Ph.D. University of California) announced a new, promising, greyish-colored antibiotic which he called neomycin. Like streptomycin, it is derived from actinomycetes. a group of tiny organisms that are in a twilight evolutionary zone between molds and bacteria. The first preliminary tests made since it was developed last summer look good; it may, eventually, prove better than streptomycin. Dr. Waksman and Hubert A. Lechevalier, a graduate student who worked with him, reported their discovery in Science...
...Golden Bug. In the test tube, neomycin worked against strains of tuberculosis bacilli which might become resistant to streptomycin (i.e., learn how to flourish alongside streptomycin). The bacilli did not become resistant to neomycin as they had to the older drug. Tests with animals are not yet complete, because there has not been enough of the stuff to work with. But in mice and on embryos from chicken eggs it worked against Staphylococcus aureus (the "golden bug" which causes boils and abscesses) and against Salmonella schottmülleri (which causes a kind of paratyphoid fever). One bug is affected...
...trouble with streptomycin is that it may make patients dizzy. So far, the new neomycin has had only a slight harmful effect, or none at all, on laboratory animals. Like penicillin, neomycin may possibly work when taken by mouth. Streptomycin must be injected. But headline writers who shout that neomycin is already a better drug for tuberculosis than streptomycin get a pained look from Dr. Waksman. He does not know yet when tests on human patients can get started...