Word: streptomycin
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...studies on muscular contraction, after going to Lederle concentrated on folic acid (part of the vitamin-B complex), helped develop its derivatives, teropterin and aminopterin (now being used to fight cancer), directed research that produced the new antibiotic, aureomycin (a cure for serious infections untouched by penicillin or streptomycin...
...Doctors are experimenting with at least 122 promising antibiotics. But only the Big Two-penicillin and streptomycin-are widely used on human patients. Runners-up: Aerosporin, chloromycetin, bacitracin, polymixin, gramicidin...
...Aerosporin, newly discovered by the research team of Dr. George Brownlee at Wellcome Laboratory, England, is: 1. A new fertilizes which hastens plant growth. 2. A new antibiotic which proved in tests many times more effective than streptomycin. 3. A new drug which helps keep pilots of supersonic planes from "blacking out." 4. The cohesive substance which keeps atomic particles together. 5. A hitherto-undetected element existing only in the stratosphere...
...Streptomycin, like penicillin, but unlike aerosporin (TIME, Feb. 23), has dangerous effects that are probably inherent, and not due to impurities. Streptomycin may cause headaches, skin eruptions, dizziness, may damage kidneys or ears...
...advantage of aerosporin: thus far bacteria have had a hard time developing resistance to it. One drawback: like streptomycin and other antibiotics, it may cause slight damage to the kidneys. Dr. Brownlee is sure that the kidney damage is caused by an impurity, which can eventually be removed. Meantime, the impurity is counteracted by an amino acid...