Word: streptomycinate
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Dates: during 1940-1949
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...front campus" before famed old Nassau Hall. There, 6,000 spectators, seated in shadows under Princeton's elms ("An adorable place, is it not?" Woodrow Wilson used to say), cheered whenever they recognized a celebrity. There were, besides Home-Towner Albert Einstein, Selman Abraham Waksman, the discoverer of streptomycin...
Retreat. The bad news was that the great hopes placed in the "wonder drug," streptomycin, as a T.B. cure have not entirely materialized. The experts at San Francisco heard a report on the first large-scale test of streptomycin. More than 800 cases were treated by the Veterans Administration, the Army and the Navy...
...certain types of T.B.-pulmonary (lung), miliary (small spots that may scatter through the body) and meningeal (brain and spinal cord)-streptomycin seemed to help. A few patients were completely cured, many of them gained weight and felt better during the four months' treatment. But in most patients the disease remained active; many infections developed resistance to the drug; the death rate was still high (up to 90% in some forms of the disease). And on many types of T.B. the drug had no appreciable effect at all. Most discouraging finding of all was that streptomycin, in the doses...
...Passano Foundation Award (kicked in by Williams & Wilkins of Baltimore, medical publishers) went to Russian-born Dr. Selman Abraham Waksman, 59, microbiologist of Rutgers and the New Jersey Agricultural Station. Dr. Waksman is certainly a leading U.S.-authority on antibiotics. His best-known discovery (1945) was streptomycin, the antibiotic which has shown most promise in the fight against tuberculosis. Early this year he persuaded his favorite mold (Actinomyces griseus) to produce another antibiotic (TIME, Feb. 10). The new one, "grisein," teams up efficiently with streptomycin (in the test tube) to fight a variety of stubborn bacteria...
...Streptomycin still looks like the most promising foe of tuberculosis, but Dr. Alfred Marshak of the U.S. Public Health Service found another likely-looking one: a yellow crystal extracted from California Spanish moss (not to be confused with the lacy Spanish moss that hangs from trees). It checks T.B. in guinea pigs, has still to be tested...