Word: streptomycinate
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...what drugs a Liberian freighter is required to carry. The doctor wrote out a message: Tea and Mineral Water. "Keep the patient in bed with absolute rest. Apply linseed poultices continuously on the swollen jaw. Give intramuscular injection of 500,000 units of penicillin combined with half gram of streptomycin morning and evening. Give only weak tea, orange juice, mineral water for 24 hours." After two days the Henri G. reported: "Patient seems better this morning. Yesterday evening pulse go fever 102 this morning pulse 70 temperature 98.6.'' More exchanges followed. Finally the Henri...
...Tests of blood and pus samples, drawn from an inflamed abscess on the child's right hip, produced a chilling diagnosis: Staphylococcus aureus, of the dreaded "hospital type,"* which is resistant to penicillin and most antibiotics. With little hope of success, physicians administered massive doses of penicillin and streptomycin. Neither worked, and the child hovered near death. Finally, doctors tried an experimental drug, one so new that it still had no name, bore only a laboratory code number: BRL 1241. The dramatic result: after five days of treatment with BRL 1241, virulent staph germs had disappeared from the infant...
...striking drop in TB mortality in the last few years (to about 12,000 in 1959) has been brought about by treatment with one or more of three wonder drugs: streptomycin (1944), para-amino-salicylic acid or PAS (1944) and isoniazid (1951). Eradication of the disease depends on full use of drugs, following aggressive case finding. There are now 400,000 known TB victims in the U.S. (150,000 with active disease), and an estimated additional 400,000 who have escaped detection...
...seven wards they put an outright ban on all the most cherished antibiotics (penicillin, streptomycin, three tetracyclines, chloramphenicol, erythromycin and novobiocin) unless the doctors could show that one of these drugs was unquestionably the best for the patient's disease. Then they had to give their first-choice antibiotic in combination with a second, to cut down the microbes' chance to develop resistance. Penicillin, as the drug previously most abused, was put under special restrictions: on some wards it could not be given at all, and when used, it had to be injected on a side ward...
...antibiotics industry has also produced spectacular ideas. Only a few years ago, Chas. Pfizer & Co. was dumping the residue of its streptomycin fermentation vats in the Wabash River. Then Pfizer and other antibiotics companies found that the residue contained vitamin B12, a powerful growth stimulant. Once, B-12 was extracted from animal livers for humans and sold for thousands of dollars an ounce. Now Pfizer sells the B-12-rich residue cheaply to feed companies, which put it into animal rations. Merck & Co. and others have synthesized gibberellic acid, which has a powerful growth-stimulating effect on plants. Minute traces...