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...locus coeruleus is indeed malfunctioning in autism, the problem could involve hundreds or even thousands of genes. The researchers are careful to avoid the shooting war over what damaged those genes, suggesting that environment and toxic chemicals - but not vaccines - may have a role. They also, tellingly, think stress is involved...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...Stress is thought to have a significant impact on the ability of the locus coeruleus to regulate noradrenaline properly, and Mehler and Purpura cite an improbable 2008 study published in the Journal of Autism and Developmental Disorders showing that mothers who lived through a hurricane during their pregnancy - particularly at the mid-gestational point - had a greater likelihood of giving birth to an autistic child than other women. "What would be involved here would be the mother's level of [the stress hormone] cortisol," says Purpura. "Between fetus and mother, the placenta acts as a very good barrier for maternal...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...theory, that blast of stress chemistry could alter the development of the fetal locus coeruleus, though Purpura is quick to point out that the study showing how cortisol can make it through the placenta was conducted in animals, not humans. Nonetheless, one day after their article in Brain Research Reviews was published, the journal Psychoneuroendocrinology published a study linking cortisol imbalance to Asperger's syndrome, a condition along the autism spectrum...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...predictably, many students are crying foul at this announcement as a missed opportunity for further College-directed programming opportunities. A stress-free break—what seemed for me to be the crown jewel of calendar reform—has irrationally become, in the eyes of my peers, yet another epic administrative blunder...

Author: By James A. Mcfadden | Title: Give Me a Break | 4/7/2009 | See Source »

...Budget estimates are wrong, so are the "stress test" assumptions for the government's new program to determine which banks are in reasonable shape to make it through the recession and which are not. The test is based on unemployment reaching as high as 10%. If the number is likely to go well beyond that, the premise for evaluating the strength of key pillars of the financial system is deeply flawed before the evaluation process has been finished. The Administration wants to set measurements for whether large American private banks need to raise money. If 10% unemployment is a critical...

Author: /time Magazine | Title: Why the Stimulus and Bailout Hit the Government | 4/6/2009 | See Source »

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