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...protein folds is determined by the sequence of amino acids that constructs it. The human body has 20 amino acids that can be arranged in any way by the polar forces of water, an abundant compound in cells. Shakhnovich’s model can predict how a certain string of amino acids will fold into a three-dimensional shape with unprecedented accuracy. The team conducted 4,000 simulations that proved to be consistent with experimental results. The biological function of a protein is then decided by the resulting structure. Through the new computer program, then, Shakhnovich and the scientific community...

Author: By Nathaniel S. Rakich, CONTRIBUTING WRITER | Title: Chemisty Prof Authors Protein Folding Program | 11/14/2006 | See Source »

Herding cats. Pushing a string. Making yourself heard in a preschool where no one has had a nap. The analogies that have been used to describe what it's like to be in charge of Congress have always suggested that the titles Speaker of the House and Senate majority leader were someone's idea of a joke. But now that the high fives and jubilant photo ops are behind them, Nancy Pelosi and Harry Reid have to run the place. Whether anything is actually accomplished on Capitol Hill over the next two years will depend largely on the skills these...

Author: /time Magazine | Title: The New Congress: Can the Democrats Get Anything Done? | 11/12/2006 | See Source »

After a seesawcareer at the University of Michigan, Tom Brady joined the New England Patriots as a fourth-string quarterback in 2000. He practiced with a group of rookies, "many of whom already had one foot in a liquor distributorship back home," writes Pierce in this bright biography. But soon Brady was guiding an unlikely dynasty, winning three Super Bowls for a downtrodden franchise. Pierce traces the sources of Brady's trademark selflessness, from growing up with three elder sisters to his struggles at Michigan. "If you choose to put yourself apart," Brady says, "you know, play tennis...

Author: /time Magazine | Title: 5 Sports Books That Deserve Big Cheers | 11/12/2006 | See Source »

...Clan, he was the group’s loosest cannon, a wild man whose erratic and self-destructive behavior was reflected in his primitive, off-balance, and completely singular microphone style. He lived the life and died to prove it: when he overdosed in 2004, he left behind a string of convictions, 13 children, and one of the most brilliantly chaotic legacies in hip-hop. His music, always disordered, has never been far from complete disaster: on “A Son Unique,” his first formal posthumous release, madness has finally vanquished method. The album begins with...

Author: By Tom C. Denison, CRIMSON STAFF WRITER | Title: NEW MUSIC: ODB | 11/8/2006 | See Source »

After ending its string of home games on a high note, Harvard will head to Cornell this Friday for conference match...

Author: By Courtney D. Skinner, CONTRIBUTING WRITER | Title: Crimson Nets First Victory | 11/7/2006 | See Source »

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