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Word: subfactor (lookup in dictionary) (lookup stats)
Dates: during 1963-1963
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Usage:

...heart, between its upper and lower left chambers. Without such an operation, Mrs. Mauldin was not likely to live long. But the N.J.H. surgeons found they could not operate because Patient Mauldin would need transfusions during surgery, and she had rare, unmatchable blood: type A (common), but with a subfactor known as RL² (uncommon) and two other mysterious subfactors which, together, would destroy any blood that she might receive by transfusion. Reluctantly, the N.J.H. surgeons sent Lila Mauldin home...

Author: /time Magazine | Title: Hematology: Saved by Her Own Blood | 11/29/1963 | See Source »

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