Word: subs
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...cutting-edge clubs, vintage- clothing stores and alternative newspapers. They are also far enough away from New York City and Los Angeles to consider themselves cool, and uncorporate enough to make room for the strikingly unconventional. A homegrown record label can make a huge difference too, like Seattle's Sub Pop, which produced Nirvana's early recordings. Ultimately, it's the big national labels that cash in on local sounds. Primed by their success with Seattle, the record companies are now grazing hungrily in college towns, those intrinsically hip places where collective shoe preference may run the narrow gamut from...
...Seattle's Sub Pop Records was founded in 1986 to capture the musical moment, market it and move on to the next moment. Sub Pop co-founders Jonathan Poneman and Bruce Pavitt envisioned their small record company as a kind of Motown of the Pacific Northwest. "The problem with the music industry in the '80s was that the major labels had their doors shut to new ideas," says Pavitt, who used to work for Muzak, the elevator-music company...
...leaked into surrounding rivers and topsoil. Inhabitants of the Vaucluse department were ordered to refrain from drinking water, eating locally caught fish, and irrigating crops with potentially contaminated water. The water prohibition remains in effect for thousands of parched locals as inspections lumber on. "We're being treated like sub-citizens," protested Yves Beck, mayor of neighboring town Bollène to the AFP. Qualifying what he called slow and unsympathetic response of authorities to the situation "unacceptable," Beck warns legal action for hardship and losses suffered may be taken. "We've told residents of Boll...
...cells. Scientists had previously studied this genetic variant - found almost exclusively in Africans and their descendants - because it also conferred protection against an early form of malaria. (The malaria parasite needed the receptor to infect blood cells; without the receptor, the parasite starved and died.) More than 90% of sub-Saharan Africans lack the red-blood-cell receptor, along with two-thirds of African-Americans. But the variant that once saved its carriers from one disease now appears to make them more susceptible to another. According to the paper, people with the gene variant were 40% more likely to become...
...exactly why," Weiss says. And though the effect of this gene variant, if confirmed, could help explain a huge number of HIV infections, it still cannot come close to explaining the AIDS burden of Africa. Nearly 70% of all HIV-positive people in the world live in sub-Saharan Africa, and prevalence rates in adults in some African countries top 20%. What's more, the gene variant is most common in West Africa, but HIV-infection rates in that region remain very low compared to those in Eastern and Southern Africa, where the disease has festered longest - and where government...