Word: subset
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Dates: during 2000-2009
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...molecular switches lie in the noncoding regions of the genome--once known dismissively as junk DNA but lately rechristened the dark matter of the genome. Much of the genome's dark matter is, in fact, junk--the residue of evolutionary events long forgotten and no longer relevant. But a subset of the dark matter known as functional noncoding DNA, comprising some 3% to 4% of the genome and mostly embedded within and around the genes, is crucial. "Coding regions are much easier for us to study," says Carroll, whose new book, The Making of the Fittest: DNA and the Ultimate...
...motor neurone disease - go home and write your will,'" says Sydney neurologist Matthew Kiernan. "The specialist didn't like looking after these patients because he knew he had nothing to offer them." There were cracks of light in the 1990s, when researchers implicated a genetic mutation in a small subset of MND patients, and the pharmaceutical company Rhone-Poulenc Rorer launched riluzole (Rilutek), the first - and still only - drug approved for treating the disease. But no one was fooled into thinking that MND was anywhere near beaten...
...Parker Palmer so aptly put it, is that we tend to “think the world apart,” treating each subject as if it should be examined within a bubble. Core classes too often fill us with names, dates, formulas, and theories for some infinitesimally small subset of a field’s body of knowledge rather than teaching us how these facts can be applied to our general understanding of the body as a whole, much less other disciplines. At the very best, Cores tend to be structured as if “ways of approaching...
...want to start this column with a shout-out to a small and oft-ignored subset of my readers. I don’t mean residents of Pfoho or my aunts down in New Jersey, though I’m glad they’re reading too. Instead, I want to acknowledge my as-of-this-writing-unborn grandchildren. I want to do this because it occurred to me recently that some day, as my distant kin are sitting in their dorm rooms in Allston looking out onto their gorgeous new student center (or, heaven forbid, envying it from somewhere...
...deciding which patients with ER-positive tumors should receive chemotherapy in addition to hormone treatments, Garber said. “We do have some sense of which of the patients with ER+ patients benefit from chemotherapy. We need to do more research to define better this subset,” Winer wrote in an e-mail. Garber said that the study will not change treatment in the short-term. “This paper will not change treatment today, but it should make us challenge everything we thought we knew,” she said...