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...year later, Yamanaka followed up his work by reporting success with the same four factors in turning back the clock on human skin cells. At about the same time, in Wisconsin, Thomson achieved the same feat using a different cocktail of genes. With those studies, what became known as induced pluripotent stem cells (iPS cells) were suddenly a reality. Never mind the frustratingly fickle process needed to create embryonic stem cells; this was something any molecular-biology graduate student could do. "We figured somebody would have success with reprogramming. We just thought that somebody would come along a generation from...

Author: /time Magazine | Title: Stem-Cell Research: The Quest Resumes | 1/29/2009 | See Source »

...Mattel isn't about to give up on one of the industry's most enduring success stories. But it is breaking out the marketing Botox. To revitalize the line, the world's largest toy company is not only adding some edge to Barbie's nonthreatening image, it is pitching Barbie-branded merchandise to a wider customer base - adults - and ramping up its overseas sales efforts, starting with the potentially vast China market, by opening dedicated Barbie concept stores (think Nike Store, but exceedingly pink). (See pictures of China's wild side...

Author: /time Magazine | Title: Botox for Barbie | 1/29/2009 | See Source »

...success of this little movie that could a matter of luck or brains or deceit? Maybe what Slumdog says about its hero applies to the film itself. Maybe it's destiny...

Author: /time Magazine | Title: From Slumdog to Top Dog | 1/29/2009 | See Source »

...three years into his premiership, the real Nouri al-Maliki may finally be revealing himself. Emboldened by his popular campaign against the Shi'ite militias, and by the U.S. military's success in turning the Sunni insurgency against al-Qaeda, Maliki has begun to project a persona instantly familiar to Iraqis, and to Arabs in general: the strongman. He has ordered the arrest of a number of prominent Sunnis, pushed aside rivals and undermined allies. In speeches, his language has grown increasingly belligerent, accusing those who disagree with his policies of working against Iraq. (See pictures of life returning...

Author: /time Magazine | Title: Nouri al-Maliki: Iraq's New Strongman | 1/28/2009 | See Source »

...Delhi views its success in avoiding becoming part of Holbrooke's diplomatic portfolio as proof of India's growing clout in Washington. Appearing on Al Jazeera, India's foreign minister, Pranab Mukherjee, evaded questions about the lobbying effort, saying only that relations between New Delhi and Washington had "increased substantially." But an official in his ministry told TIME that New Delhi is "feeling vindicated, because finally the U.S. has given us the respect we deserve...

Author: /time Magazine | Title: Will Kashmir Be an Obama Foreign Policy Focus? | 1/28/2009 | See Source »

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