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...class of drugs called aromatase inhibitors, which for postmenopausal women are already in use against late-stage tumors and may prove even more effective when tumors are caught early. Aromatase inhibitors block the action of an enzyme that these women need to produce estrogen. Two new studies suggest that the drugs can shrink tumors before surgery and also perhaps prevent breast cancer from recurring. More than 20,000 women are enrolled in clinical trials designed to show just how effective the aromatase inhibitors are in early cancer and how best to use them...

Author: /time Magazine | Title: Prevention: Estrogen: A Villain And A Possible Savior | 2/18/2002 | See Source »

Meanwhile, researchers are getting better at predicting who is most likely to benefit from which designer estrogen. Raloxifene, it turns out, is most effective for the postmenopausal women who have naturally high levels of estrogen. Other tests suggest that tamoxifen offers little or no benefit to women who carry the BRCA1 mutation, one of two genetic mutations known to cause an inherited form of breast cancer, but it can help lower the risk of breast cancer in women carrying a variation of the gene called BRCA2. For now, women who are taking tamoxifen should continue doing...

Author: /time Magazine | Title: Prevention: Estrogen: A Villain And A Possible Savior | 2/18/2002 | See Source »

...exerts an appeal to those born into the faith who feel oppressed by societies that treat them like second-class relics of European colonialism. Islam also promises something to converts-like Reid and Courtailler-who feel marginalized by modern life. For Europeans, the presence of the terrorist networks should suggest that there is something rotten within their rich societies...

Author: /time Magazine | Title: The Shoe Bomber's World | 2/16/2002 | See Source »

...food, a mere commodity. “Portrait (W. Pooh),” for instance—a bust of a chocolate bear—is absurd and self-effacing. Art, then, for Ryoo is its own subject—her photographs are a kind of meta-art. They suggest that artistic creation is subject to the same commodification as the boxes of Tide and cereal in Wing’s photographs...

Author: By D. ROBERT Okada, CONTRIBUTING WRITER | Title: MetaArt: Constructing Self-Criticism | 2/15/2002 | See Source »

...Ironically, Rajoub seemed to have learned from his boss, telling the media on Wednesday that there had been no quarrel and that to challenge Arafat "at a time when Israeli tanks are 70 meters from his office would be the height of treachery." Nonetheless, insider accounts suggest that Rajoub was essentially urging Arafat to provide public political backing for the orders he gives in private, making clear to the Palestinian rank-and-file where their leader stands. But Arafat is habitually inclined to ambiguity, which has allowed him room for the maneuvering that has been the hallmark of his more...

Author: /time Magazine | Title: Arafat's Office Brawl Signals Political Crisis | 2/14/2002 | See Source »

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