Word: sulfa
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Dates: during 1960-1969
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Herculean Check. Acting on the advice of such specialists and on his own preferences, Goddard brusquely reversed Sadusk in a drumfire series of decisions which drastically restricted the use of long-acting sulfa drugs, attacked the inflated advertising for Peritrate (a painkiller for angina pectoris), and flatly forbade the further manufacture of over-the-counter throat lozenges containing antibiotics. He also promised a congressional committee that FDA would promptly tackle the herculean task of checking the efficacy of 3,000 drugs marketed between...
...physicians should be free to make their own choices from among many available drugs, all of which have some degree of danger. His opponents now accuse him of betraying the public interest in favor of protecting the pharmaceutical manufacturers. Some recent examples of action, inaction and disputed decisions: ≫ SULFAS. FDA last week announced that it was requiring new labeling on two long-acting sulfa drugs marketed by three firms,* "to warn against rare cases of a severe and sometimes fatal side effect," a blistering and ulceration known as the Stevens-Johnson syndrome. There have been 81 reported U.S. cases...
Died. Dr. Perrin Hamilton Long, 66, professor of preventive medicine at Johns Hopkins Medical School from 1940 to 1951 and the man credited with a major role in popularizing the use of sulfa drugs in the U.S., who in 1936 heard reports of the anti-infection properties of a sulfa-derivative German dye, carried out his own experiments on sulfanilamide, thus raising the curtain on the age of wonder drugs; of a heart attack; in Edgartown, Mass...
...malaria discipline, the Department of Defense reports that ten Americans have died in Viet Nam this year from cerebral or other complications, and researchers are intensifying the hunt for new drugs. One that shows some promise is DOS (diaphenylsulfone), normally used in leprosy. Another is a new, long-acting sulfa drug, Fanasil. Malariologists are running tests with prison volunteers to see whether DDS or Fanasil can be used, probably in combination with pyrimethamine, to beat back the chloroquine resistance of falciparum parasites in much of Southeast Asia...
Because burns are among the most common disfiguring, crippling and fatal accidents, physicians and surgeons have tried almost every imaginable therapy. In the 100 years since Lister discovered asepsis, practitioners have hopefully tried phenol, boric acid, picric acid, iodoform, tannic acid, sulfa drugs and ACTH, only to wind up, after a few years, disappointed in all of them. Now another new and seemingly miraculous treatment has been discovered, and once again doctors are hopeful-this time with better reason...