Word: sulfa
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...painful, I cut it with a penknife. This did not cure it. The village barber told me to apply lime and tobacco. It got worse and I tried a local remedy, covering up the sore with mud. That did not do any good, either." The student put on a sulfa dressing, told Sriramulu he was lucky not to have developed tetanus...
Appendicitis is no longer the killer it was a dozen years ago. Since sulfa drugs began to be used to control the complication of peritonitis, the annual toll of U.S. lives lost to appendicitis has been cut from about 17,000 to 5,000. But, says Dr. Frederick Fitzherbert Boyce of New Orleans, the success of the wonder drugs has given both doctors and laymen a false sense of security...
...over a two-year period in the treatment of 7,000 patients. And behind its discovery and development was the potent name of Professor Gerhard Domagk, 54, who won fame-and a 1939 Nobel Prize, which the Nazis would not let him take-as top man in perfecting the sulfa drugs...
...dreaded diseases are caused by microorganisms, scientists have searched for a drug that would kill the little villains without damaging the tissues of their human victims. A few chemical drugs were synthesized. Salvarsan, "606," developed by Ehrlich, proved to be effective against syphilis. Much later, in 1935, came the sulfa drugs, the medical wonders of their day. But none of the chemical "magic bullets" was effective against more than a few disease organisms, and all of them were apt to have dangerous toxic effects on human tissues...
Doctors are keenly aware that the antibiotics (sulfa drugs, penicillin, streptomycin, etc.) have two great dangers: 1) sometimes the drug has a poisonous effect on the patient, and 2) the bacteria under attack may develop a tolerance for the drug. Last week doctors at the 13th Congress of the International Society of Surgery in New Orleans were reminded of another danger: antibiotics speed up the clotting time of the blood, thus subject the patient to the risk of death from blood clots forming, breaking loose, and being carried through the heart into the lungs...