Word: sulfa
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...Unlike sulfa drugs, penicillin has not yet shown any harmful effects. A patient's appetite often increases; his anemia may improve...
...Sulfa drugs characteristically produce sudden drops in body temperature, but less spectacular penicillin, which may take weeks to save a life, usually reduces temperature by easy stages...
...When a sulfa drug comes along, some ordinarily susceptible bacteria do not just lie down and take it. Some of them develop such resistance that they can even multiply in the presence of the enemy. Up to now, laboratory workers have been unable to prove how a resistant strain differs from a susceptible one of the same species. They look alike, grow alike, form the same kind of colonies...
...Science last week Maurice Landy and coworkers of the Army Medical School in Washington announced that they had used the test with positive results: a resistant strain of Staphylococcus aureus (pus bacteria) was definitely making more PAB than its sulfa-susceptible twin. They attributed its sulfa-resistance to the PAB -possibly a big step forward in chemotherapy...
Experiments have already shown that penicillin attacks certain bacteria more successfully than sulfa drugs do. Unlike sulfa drugs, penicillin's effects are not inhibited by pus and other materials formed in infected wounds. Used in low concentrations in the blood stream, penicillin's action is bacteriostatic, i.e., it prevents bacteria from multiplying and renders them easy prey for white blood corpuscles. Penicillin solutions strong enough to kill bacteria may safely be injected under the skin near a wound or used as a dressing...